WUR - Wageningen University & Research

IBISBA is designed to accelerate end-to-end bioprocess development, linking best-in-class R&D facilities to provide seamless multi-technology services.

Focusing on the different R&D phases in bioprocess development, IBISBA offers services related to computer-assisted design of biocomponents, construction of enzymes and microbial strains, the fermentation, downstream processing and project knowledge asset management.

Horizon Europe is the EU’s main funding program for research and innovation from 2021 to 2027. It tackles climate change, helps to achieve the UN’s Sustainable Development Goals and boosts the EU’s competitiveness and growth. The programme facilitates collaboration and strengthens the impact of research and innovation in developing, supporting and implementing EU policies while tackling global challenges. It supports creating and better dispersing of excellent knowledge and technologies. It creates ...

IBISBA-DIALS: IBISBA - Delivering the Infrastructure As a Legal Structure

A solution to industrial biotechnology's barriers

In the quest for sustainable, circular economies, industrial biotechnology is a game-changer. However, unlocking its full potential hinges on addressing complex challenges and streamlining research and innovation (R&I). In this context, the EU-funded IBISBA-DIALS project aims to reshape the R&I landscape by establishing a European Research Infrastructure ...

Real-time online monitoring of bioprocesses

Industrial biotechnology (IB) has the potential to create new markets while protecting the environment. With this in mind, the EU-funded BIOINDUSTRY 4.0 project will pave the way for IB to become a major manufacturing technology. Supporting the digitalisation of IB, the project will create new services delivered by European research infrastructure. These will address several challenges, focusing on the acceleration of bioprocess development pipelines. ...

This programme is for making IBISBA documents available to the public.

Artificial intelligence (AI) and machine learning (ML) models as well as Digital shadows and Digital twins as well as Digital shadows and Digital twins have been, and are being, developed for a variety of applications, including industrial process supervision, bioprocess optimization, energy management, and environmental monitoring. In cases where models have the aim to classify, predict, or forecast a variable of interest then these models must become deployable in real-time so that their ...

Use case of Pseudomonas putida

This project make available the deliverables of the PREP-IBISBA project

This project collects together the IBISBA 1.0 deliverables

Industrial-scale penicillin simulation

Industrial-scale penicillin simulation (IndPenSim) is a first principles mathematical model of a 100,000 Litre fermentation of an industrial strain of Penicillium chrysogenum validated using historical data collected from an industrial-scale penicillin fermentation process. Adapting a previously published structured model to describe penicillin fermentation and extending the model to include the main environmental effects of dissolved oxygen, ...